ATE6501T1 - Verfahren zur herstellung von 1-isopropylamino-3(4-(2-methoxy[thyl)-phenoxy)-2-propanol. - Google Patents
Verfahren zur herstellung von 1-isopropylamino-3(4-(2-methoxy[thyl)-phenoxy)-2-propanol.Info
- Publication number
- ATE6501T1 ATE6501T1 AT81200616T AT81200616T ATE6501T1 AT E6501 T1 ATE6501 T1 AT E6501T1 AT 81200616 T AT81200616 T AT 81200616T AT 81200616 T AT81200616 T AT 81200616T AT E6501 T1 ATE6501 T1 AT E6501T1
- Authority
- AT
- Austria
- Prior art keywords
- phenoxy
- isopropylamino
- propanol
- methoxy
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N 2-propanol Substances CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 title 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 2
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 abstract 2
- CTZFISYPUSQFRR-UHFFFAOYSA-N [1-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]-2-methoxyethyl] acetate Chemical compound COCC(OC(C)=O)C1=CC=C(OCC(O)CNC(C)C)C=C1 CTZFISYPUSQFRR-UHFFFAOYSA-N 0.000 abstract 1
- TXXKLRMEPRZIPQ-UHFFFAOYSA-N [2-methoxy-1-[4-(oxiran-2-ylmethoxy)phenyl]ethyl] acetate Chemical compound C1=CC(C(OC(C)=O)COC)=CC=C1OCC1OC1 TXXKLRMEPRZIPQ-UHFFFAOYSA-N 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical compound CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 abstract 1
- 229940098779 methanesulfonic acid Drugs 0.000 abstract 1
- IUBSYMUCCVWXPE-UHFFFAOYSA-N metoprolol Chemical compound COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 IUBSYMUCCVWXPE-UHFFFAOYSA-N 0.000 abstract 1
- 229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
- 239000012279 sodium borohydride Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI801792A FI801792A7 (fi) | 1980-06-04 | 1980-06-04 | Menetelmä terapeuttisesti aktiivisen propanoliamiinin valmistamiseksi. |
| FI803119A FI63016C (fi) | 1980-06-04 | 1980-10-01 | Foerfarande foer framstaellning av en terapeutiskt aktiv propanolamin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE6501T1 true ATE6501T1 (de) | 1984-03-15 |
Family
ID=26157125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT81200616T ATE6501T1 (de) | 1980-06-04 | 1981-06-03 | Verfahren zur herstellung von 1-isopropylamino-3(4-(2-methoxy[thyl)-phenoxy)-2-propanol. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0041760B1 (en]) |
| JP (1) | JPH0314547A (en]) |
| AT (1) | ATE6501T1 (en]) |
| DK (1) | DK153144C (en]) |
| FI (1) | FI63016C (en]) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3360426D1 (en) * | 1982-04-08 | 1985-08-29 | Beecham Group Plc | N-substituted derivatives of ethanol amine |
| US11957663B1 (en) | 2023-10-31 | 2024-04-16 | King Faisal University | 3-(2,4,5-tris(4-chlorophenyl)-1H-imidazol-1-yl) propanoic acid as an antimicrobial compound |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE354851B (en]) * | 1970-02-18 | 1973-03-26 | Haessle Ab |
-
1980
- 1980-10-01 FI FI803119A patent/FI63016C/fi not_active IP Right Cessation
-
1981
- 1981-06-03 EP EP81200616A patent/EP0041760B1/en not_active Expired
- 1981-06-03 AT AT81200616T patent/ATE6501T1/de not_active IP Right Cessation
- 1981-06-03 DK DK243481A patent/DK153144C/da not_active IP Right Cessation
-
1990
- 1990-05-25 JP JP2136936A patent/JPH0314547A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FI63016C (fi) | 1983-04-11 |
| JPH0333699B2 (en]) | 1991-05-20 |
| FI803119L (fi) | 1981-12-05 |
| DK153144B (da) | 1988-06-20 |
| FI63016B (fi) | 1982-12-31 |
| DK153144C (da) | 1988-10-31 |
| DK243481A (da) | 1981-12-05 |
| EP0041760A1 (en) | 1981-12-16 |
| JPH0314547A (ja) | 1991-01-23 |
| EP0041760B1 (en) | 1984-03-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |